Neonatal Brain Development and Injury
Rapid medical and technological advances have significantly improved the survival of preterm babies and term neonates with brain injury of environmental (e.g. hypoxia) or genetic causes.
The focus of the lab is to understand the molecular mechanisms underlying neurodevelopmental disorders associated with fetal and neonatal brain injury with the long-term goal of translating the lab’s findings into therapeutics.
The research team uses region-specific human brain organoids differentiated from induced pluripotent stem cells (hiPSC) and employs a multidisciplinary approach involving genetics, molecular and developmental neurobiology and multi-omics to ask questions about brain injury during development.